Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease 1 Strains . 2 3 4
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Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains.
UNLABELLED Transmission of chronic wasting disease (CWD) between cervids is influenced by the primary structure of the host cellular prion protein (PrP(C)). In white-tailed deer, PRNP alleles encode the polymorphisms Q95 G96 (wild type [wt]), Q95 S96 (referred to as the S96 allele), and H95 G96 (referred to as the H95 allele), which differentially impact CWD progression. We hypothesize that the...
متن کاملDeer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease
Text word count (4173) 19 20 21 22 JVI Accepted Manuscript Posted Online 30 September 2015 J. Virol. doi:10.1128/JVI.02010-15 Copyright © 2015 Duque Velásquez et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any mediu...
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